Article added / Artikel hinzugefügt 22.05.2018

"Evaluation of P16 expression in canine appendicular osteosarcoma"

Article added / Artikel hinzugefügt 21.05.2018

"Evaluation of Weight Change During Carboplatin Therapy in Dogs With Appendicular Osteosarcoma"

Article added / Artikel hinzugefügt 21.05.2018

"Pedicle frozen autograft for limb sparing surgery in a dog with femoral osteosarcoma"

Article added / Artikel hinzugefügt 16.05.2018

"Long-term Formation of Aggressive Bony Lesions in Dogs with Mid-Diaphyseal Fractures Stabilized with Metallic Plates: Incidence in a Tertiary Referral Hospital Population"

Article added / Artikel hinzugefügt 30.03.2018

"Prognostic factors of early metastasis and mortality in dogs with appendicular osteosarcoma after receiving surgery: An individual patient data meta-analysis"

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Ultrasonography of Osteosarcoma in Dogs
Sonography Atlas of Dogs

Generally Articles and Discussions about Osteosarcoma in Dogs

(Allgemeine Artikel und Diskussionen über Osteosarkome beim Hund)

Evaluation of P16 expression in canine appendicular osteosarcoma................................................................................

Evaluation of Weight Change During Carboplatin Therapy in Dogs With Appendicular Osteosarcoma........................

Pedicle frozen autograft for limb sparing surgery in a dog with femoral osteosarcoma.................................................

Long-term Formation of Aggressive Bony Lesions in Dogs with Mid-Diaphyseal Fractures Stabilized with Metallic Plates: Incidence in a Tertiary Referral Hospital Population.............................................................................................

Prognostic factors of early metastasis and mortality in dogs with appendicular osteosarcoma after receiving surgery: An individual patient data meta-analysis........................................................................................................

Identification of myeloid derived suppressor cells in the peripheral blood of tumor bearing dogs............................

Clinical and Immunomodulatory Effects of Toceranib Combined with Low-Dose Cyclophosphamide in Dogs with Cancer.........................................................................................................................................................................................

A Comparison of Five Different Bone Resorption Markers in Osteosarcoma-Bearing Dogs, Normal Dogs, and Dogs with Orthopedic Diseases......................................................................................................................................

Decreased Ratio of CD8+ T Cells to Regulatory T Cells Associated with Decreased Survival in Dogs with Osteosarcoma..........................................................................................................................................................

Canine Osteosarcoma: A Naturally Occurring Disease to Inform Pediatric Oncology.....................................................

Surface Antigens between Histiocytic and Nonhistiocytic Sarcoma in Dogs....................................................................

Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior.....

Prospective PreliminaryIn Vitro Investigation of a Magnetic Iron Oxide Nanoparticle Conjugated with Ligand CD80 and VEGF Antibody As a Targeted Drug Delivery System for the Induction of Cell Death in Rodent Osteosarcoma Cells.................................................................................................................................................

DNA damage response and DNA repair – dog as a model?................................................................................................

ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma....................................................................

Evaluation of Weight Change During Carboplatin Therapy in Dogs With Appendicular Osteosarcoma........................

A Dog in the Cancer Fight: Comparative Oncology in Osteosarcoma.................................................................................

Osteosarcoma in Dogs: Diagnosis and Treatment - A Literature Review...........................................................................

Fine Needle Aspiration: Osteomyelitis and Osteosarcoma in Dogs...................................................................................

Manipulation of Innate Immunity for Cancer Therapy in Dogs............................................................................................

The Use of Naturally Occurring Cancer in Domestic Animals for Research into Human Cancer: General Considerations and a Review of Canine Skeletal Osteosarcoma.....................................................................

Evaluation of the adverse event profile and pharmacodynamics of toceranib phosphate administered to dogs with solid tumors at doses below the maximum tolerated dose.................................................................................

Hyperthermic Isolated Limb Perfusion with TNF α and Cisplatin in the Treatment of Osteosarcoma of the Extremities: A Feasibility Study in Healthy Dogs.....................................................................................................

Genome-Wide Analyses Suggest Mechanisms Involving Early B-Cell Development in Canine IgA Deficiency............

Evidence supporting the conceptual framework of cancer chemoprevention in canines.............................................

The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines....................................................................................................................

Characterization of STAT3 activation and expression in canine and human osteosarcoma...........................................

MiR-9 is overexpressed in spontaneous canine osteosarcoma and promotes a metastatic phenotype including invasion and migration in osteoblasts and osteosarcoma cell lines..............................................................................

Genomic Instability and Telomere Fusion of Canine Osteosarcoma Cells........................................................................

Combination Therapy with Zoledronic Acid and Parathyroid Hormone Improves Bone Architecture and Strength following a Clinically-Relevant Dose of Stereotactic Radiation Therapy for the Local Treatment of Canine Osteosarcoma in Athymic Rats................................................................................................................................

Expression of Snail2 in long bone osteosarcomas correlates with tumour malignancy..................................................

Stem cell growth factor receptor in canine vs. feline osteosarcomas................................................................................

Phase I Evaluation of STA-1474, a Prodrug of the Novel HSP90 Inhibitor Ganetespib, in Dogs with Spontaneous Cancer.....................................................................................................................................................................................

Fluoroquinolone-Mediated Inhibition of Cell Growth, S-G2/M Cell Cycle Arrest, and Apoptosis in Canine Osteosarcoma Cell Lines..........................................................................................................................................

Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines..............

Coccidioidomycosis in Biopsies with Presumptive Diagnosis of Malignancy in Dogs: Report of Three Cases and Comparative Discussion of Published Reports................................................................................................................

Snail2 promotes osteosarcoma cell motility through remodelling of the actin cytoskeleton and regulates tumor development..........................................................................................................................................................................

Oxidative stress in cancer-bearing dogs assessed by measuring serum malondialdehyde...........................................

Imaging and surgical outcomes of spinal tumors in 18 dogs and one cat.........................................................................

Downregulation of CXCR4 Expression and Functionality After Zoledronate Exposure in Canine Osteosarcoma.......

Combinatorial Treatment of DNA and Chromatin-Modifying Drugs Cause Cell Death in Human and Canine Osteosarcoma Cell Lines..............................................................................................................................................

Oncostatin M promotes STAT3 activation, VEGF production, and invasion in osteosarcoma cell lines........................

Kinetic, kinematic, magnetic resonance and owner evaluation of dogs before and after the amputation of a hind limb............................................................................................................................................................................................

The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line..........

Comparison of non-coding RNAs in human and canine cancer.........................................................................................

Anticancer Effects of Geopropolis Produced by Stingless Bees on Canine Osteosarcoma Cells In Vitro....................

Canine cancer immunotherapy studies: linking mouse and human..................................................................................

The Healing Process of Intracorporeally and In Situ Devitalized Distal Femur by Microwave in a Dog Model and Its Mechanical Properties In Vitro.......................................................................................................................................

Oxidative stress in cancer-bearing dogs assessed by measuring serum malondialdehyde...........................................

High dose lansoprazole combined with metronomic chemotherapy: a phase I/II study in companion animals with spontaneously occurring tumors.............................................................................................................................................

Wnt/β-Catenin Expression Does Not Correlate with Serum Alkaline Phosphatase Concentration in Canine Osteo-sarcoma Patients.......................................................................................................................................................................

Effects of epidermal growth factor receptor kinase inhibition on radiation response in canine osteosarcoma cells

A multi-site feasibility study for personalized medicine in canines with Osteosarcoma................................................

The effects of taurolidine alone and in combination with doxorubicin or carboplatin in canine osteosarcoma in vitro.........................................................................................................................................................................................

Immunohistochemical investigation of cell cycle and apoptosis regulators (Survivin, β-Catenin, P53, Caspase 3) in canine appendicular osteosarcoma......................................................................................................................................

The Association of Endothelin‐1 Signaling with Bone Alkaline Phosphatase Expression and Protumorigenic Activities in Canine Osteosarcoma.............................................................................................................................

The Golden Retriever Lifetime Study: establishing an observational cohort study with translational relevance for human health...........................................................................................................................................................................

Attenuated Semliki Forest virus for cancer treatment in dogs: safety assessment in two laboratory Beagles.............

Small-Molecule Procaspase-3 Activation Sensitizes Cancer to Treatment with Diverse Chemotherapeutics.............

Mesenchymal stem cells with rhBMP-2 inhibits the growth of canine osteosarcoma cells............................................

Blocking Signaling at the Level of GLI Regulates Downstream Gene Expression and Inhibits Proliferation of Canine Osteosarcoma Cells..........................................................................................................................................

Osteosarcoma Models: From Cell Lines to Zebrafish...........................................................................................................

Preclinical Evaluation of the Novel, Orally Bioavailable Selective Inhibitor of Nuclear Export (SINE) KPT-335 in Spontaneous Canine Cancer: Results of a Phase I Study.............................................................................................

Invasive pleural malignant mesothelioma with rib destruction and concurrent osteosarcoma in a dog......................

Identification of Myeloid Derived Suppressor Cells in Dogs with Naturally Occurring Cancer......................................

Association between Body Condition Score and Cancer Prognosis in Dogs with Lymphoma and Osteosarcoma.....

Intra- and interspecies gene expression models for predicting drug response in canine osteosarcoma...................

Suppression of vascular endothelial growth factor expression by cannabinoids in a canine osteosarcoma cell line

Association of Canine Osteosarcoma and Monocyte Phenotype and Chemotactic Function........................................

MicroRNAs at the human 14q32 locus have prognostic significance in osteosarcoma...................................................

Impact of Toceranib/Piroxicam/Cyclophosphamide Maintenance Therapy on Outcome of Dogs with Appendicular Osteosarcoma following Amputation and Carboplatin Chemotherapy: A Multi-Institutional Study

Osteosarcoma in dogs: clinical-morphological study and prognostic correlation............................................................

Spontaneous Osteosarcoma in Dogs: Diagnosis through Cytopathological and Histopathological Assays...................

Current Status and Perspectives Regarding the Treatment of Osteosarcoma: Chemotherapy.....................................

Rapamycin Pharmacokinetic and Pharmacodynamic Relationships in Osteosarcoma: A Comparative Oncology Study in Dogs........................................................................................................................................................................

Breed-Predispositions to Cancer in Pedigree Dogs..............................................................................................................

Peroxisome proliferator activated receptor γ protein expression is asymmetrically distributed in primary lung tumor and metastatic to lung osteosarcoma samples and does not correlate with gene methylation...................

Expression of Nociceptive Ligands in Canine Osteosarcoma.............................................................................................

A chondroblastic osteosarcoma of the coronoid process mimicking a fragmented coronoid process in a dog........

On the potential of oncolytic virotherapy for the treatment of canine cancers................................................................

Amputation and dexniguldipine as treatment for canine appendicular osteosarcoma.................................................

Cellular and Phenotypic Characterization of Canine Osteosarcoma Cell Lines................................................................

Intramuscular IL-12 Electrogene Therapy for Treatment of Spontaneous Canine Tumors.............................................

Comparative Aspects between Canine and Human Mesenchymal Tumors.....................................................................

Retrospective Study of 33 Dogs Diagnosed with Osteosarcoma (OSA) by Fine Needle Aspiration Cytology (FNAC) at FMVZ Vet Hospital, UNESP-Botucatu, SP.......................................................................................................................

Canine Osteosarcoma: A Review and anExperimental Treatment Regime.......................................................................

A novel derivative of doxorubicin, AD198, inhibits canine transitional cell carcinoma and osteosarcoma cells in vitro..........................................................................................................................................................................................

AAHA Oncology Guidelines for Dogs and Cats......................................................................................................................

Expression of platelet-derived growth factor BB, erythropoietin and erythropoietin receptor in canine and feline osteosarcoma............................................................................................................................................................................

Expression of Bcl-2 in canine osteosarcoma.........................................................................................................................

Arginase Treatment Prevents the Recovery of Canine Lymphoma and Osteosarcoma Cells Resistant to the Toxic Effects of Prolonged Arginine Deprivation...........................................................................................................................

Ipsilateral vascularised ulnar transposition autograft for limb-sparing surgery of the distal radius in 2 dogs with osteosarcoma.........................................................................................................................................................................

Canine spirocercosis-associated extraskeletal osteosarcoma with central nervous system metastasi........................

Targeted radiotherapy with Sm-153-EDTMP in nine cases of canine primary bone tumours........................................

Establishment and Characterization of New Canine and Feline Osteosarcoma Primary Cell Lines..............................

Verständnis der Osteosarkom Pathogenese: Ein vergleichender onkologischer Ansatz................................................

Vergleichende Aspekte der Pathogenese von Osteosarkomen bei Menschen und Hunden........................................

Knochenkrebs bei Hunden – Was ist der Stand der Praxis und welche neuen Forschungsansätze gibt es?..............

Maulhöhlentumore bei Hund und Katze: Kann Bestrahlungstherapie die lokale Tumorkontrolle verbessern?.........

Comparative Aspects of Osteosarcoma Pathogenesis in Humans and Dogs....................................................................

Understanding the Osteosarcoma Pathobiology: A Comparative Oncology Approach...................................................

Osteosarcoma.............................................................................................................................................................................

Urine N-Telopeptide Excretion in Dogs with Appendicular Osteosarcoma.....................................................................

Double-Blind Placebo-Controlled Trial of Adjuvant Pamidronate with Palliative Radiotherapy and Intravenous Doxorubicin for Canine Appendicular Osteosarcoma Bone Pain................................................................................

Evaluation of Satraplatin in Dogs with Spontaneously Occurring Malignant Tumors.......................................................

Osteosarkom...............................................................................................................................................................................

Association between Absolute Tumor Burden and Serum Bone-Specific Alkaline Phosphatase in Canine Appendicular Osteosarcoma...................................................................................................................................

Investigating TrkA Expression in Canine Appendicular Osteosarcoma..............................................................................

Treatment of Canine Appendicular Osteosarcoma Using Cobalt 60 Radiation and Intraarterial Cisplatin..................

Pro-tumorigenic Effects of Transforming Growth Factor Beta 1 in Canine Osteosarcoma.............................................

Effect of Tolfenamic Acid on Canine Cancer Cell Proliferation, Specificity Protein (Sp) Transcription Factors, and Sp-Regulated Proteins in Canine Osteosarcoma, Mammary Carcinoma, and Melanoma Cells..................................

Morphological and Immunohistochemical Characterization of Canine Osteosarcoma Spheroid Cell Cultures..........

Dasatinib Modulates Invasive and Migratory Properties of Canine Osteosarcoma and has Therapeutic Potential in Affected Dogs............................................................................................................................................................................

Doxorubicin and BAY 12–9566 for the Treatment of Osteosarcoma in Dogs: A Randomized, Double-Blind, Placebo-Controlled Study............................................................................................................................................

In vitro Effects of Canine Wharton's Jelly Mesenchymal Stromal Cells and Micellar Nanoparticles on Canine Osteosarcoma D17 Cell Viability..................................................................................................................................

Modulation of Angiogenesis and Immune Response in Canine Osteosarcoma by BMP-2 and Mesenchymal Stem Cells...........................................................................................................................................................................................

Comparison of Carboplatin and Doxorubicin-Based Chemotherapy Protocols in 470 Dogs after Amputation for Treatment of Appendicular Osteosarcoma.......................................................................................................................

Adjuvant Carboplatin and Gemcitabine Combination Chemotherapy Postamputation in Canine Appendicular Osteosarcoma.......................................................................................................................................................................

Expression profiling in canine osteosarcoma:identification of biomarkers and pathways associated withoutcome.

HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors

TPLOS and Osteosarcoma........................................................................................................................................................

Global Gene Expression Analysis of Canine Osteosarcoma Stem Cells Reveals a Novel Role for COX-2 in Tumour Initiation.....................................................................................................................................................................................

Canine tumor cross-species genomics uncovers targets linked to osteosarcoma progression.....................................

The long-acting COX-2 inhibitor mavacoxib (Trocoxil (TM)) has anti-proliferative and pro-apoptotic effects on canine cancer cell lines and cancer stem cells in vitro................................................................................................

Role of Selective Cyclo-Oxygenase-2 Inhibitor Celecoxib in Canine Osteosarcoma Cell Culture.................................

BMI1 Is Expressed in Canine Osteosarcoma and Contributes to Cell Growth and Chemotherapy Resistance..........

Gene expression profiling of canine osteosarcoma reveals genes associated with short and long survival times.....

Axial Osteosarcoma in Dog – Case Report.............................................................................................................................

The Immunotherapy of Canine Osteosarcoma: A Historical and Systematic Review......................................................

Etablierung eines kryochirurgischen Behandlungsverfahrens an Knochengewebe mittels Miniaturkryosonden und erste klinische Ergebnisse bei Osteosarkomen...............................

Genome-wide Analyses implicate 33 loci in heritable dog osteosarcoma, including regulatory variants near CDKN2A/B.......................................................................................................................................................................

Aerosol Gemcitabine: Preclinical Safety and In Vivo Antitumor Activity in Osteosarcoma-Bearing Dogs.....................

Prognostic factors in canine appendicular osteosarcoma - a meta-analysis.....................................................................

Pharmakinetic study and evaluation on the safety of taurolidine for dogs with osteosarcoma.....................................

What do we know about canine osteosarcoma treatment ? - review................................................................................

Protein kinase C regulates ezrin-radixin-phosphorylation in canine osteosarcoma cells...............................................

Osteosarkome des Hundes......................................................................................................................................................

Standardisierung der Untersuchungsverfahren bei spezifischen Schmerzbildern zur früheren Erkennung des Osteosarkoms beim Hund..................................................................................................................................................

Durchbruch in der Schmerzbehandlung für Hunde mit Osteosarkom ?..........................................................................

The effect of Zhangfei/CREBZF on cell growth differentiation,apoptosis,migration,and the unfolded protein response in several canine...........................................................................................................................................

Comparative analysis of the surface exposed proteome of two canine osteosarcoma cell lines and normal canine osteoblasts..................................................................................................................................................................................

Approaches to canine health surveillance.............................................................................................................................

Palliative Bestrahlung mit 60Co-Teletherapie beim appendikularen Osteosarkom des Hundes.................................

Zum Osteosarkom - eine vergleichende Literaturstudie.....................................................................................................

Cisplatin and doxorubicin combination chemotherapy for the treatment of canine osteosarcoma: a pilot study.....

0-7-21 Radiation Therapy for the Palliation of Advanced Cancer in Dogs.........................................................................

Canine Osteosarcoma - Treatment by Amputation Versus Amputation and Adjuvant Chemotherapy Using Doxorubicin and Cisplatin..........................................................................................................................................

Canine Osteosarcoma: A clinico-pathologic study of 194 case..........................................................................................

The Treatment of Malignant Tumours of Bone in the Dog by Intra-Arterial Injection or Perfusion of Epodyl (Triethyleneglycol Diglycidyl Ether)*.........................................................................................................................